Criteria for Histamine Achlorhydria

The augmented histamine test with special reference to achlorhydria.

The Kay augmented histamine test has been used in a special study of 30 patients with pernicious anaemia and 136 other subjects suspected of having achlorhydria. The findings have been correlated with uropepsinogen excretion, serum levels of vitamin B(12), and gastric biopsy. The definition of achlorhydria is specially considered.

Achlorhydria by ezrin knockdown

Loss of gastric acid secretion is pathologically known as achlorhydria. Acid-secreting parietal cells are characterized by abundant expression of ezrin (Vil2), one of ezrin/radixin/moesin proteins, which generally cross-link actin filaments with plasma membrane proteins. Here, we show the direct in vivo involvement of ezrin in gastric acid secretion. Ezrin knockout (Vil2(-/-)) mice did not surv...

A dye-resin test for achlorhydria.

The use of resins as a basis for "tubeless test meals " has made the unpleasant experience of aspiration of gastric contents unnecessary in many cases. A substance incorporated in the resin is released in the stomach only in the presence of free hydrochloric acid. This substance is then absorbed into the blood and excreted in the urine. Originally quinine was used in the test, and estimated flu...

Achlorhydria and Anæmia

Achlorhydria: hypergastrinaemia: carcinoids--a flawed hypothesis?